When done right, a satire pays the proper respect to its subject matter. However, a vast majority of the satire on [adult swim] falls way short of the mark.
The Venture Brothers does not. Inspired by and a satire of Jonny Quest, the series chronicles the 2nd & 3rd generations of the Venture family, as Dr. Venture is actually the son of the original, and his fraternal twin sons are the real stars of the show. However, it has taken 11 years to get to six seasons, the 3 year gap between seasons 1 & 2 caused likely by [as]' uncertainty over renewing the series. There was a 2 year gap between seasons 2 & 3, and, well, you can see the pattern.
Christopher McCullough created the series under the pen name Jackson Publick, and voices a few characters, including one of the Venture twins. Patrick Warburton (Rules of Engagement) was heard as bodyguard Brock Samson, who looked more like he belonged in a wrestling ring than as a bodyguard, for the first three seasons. There really was no reason given for Samson being written out of the show. Then again, it's [as]. Rhyme & reason are foreign concepts.
Here's the open:
Fortunately, the early seasons are out on DVD, I do believe.