It's been proven many times over that if a Saturday morning cartoon doesn't start the season on time, for whatever reason, it's doomed to fail.
Such was the case with the Olsen twins, Mary-Kate & Ashley (ex-Full House), who had made an earlier sitcom comeback (Two of a Kind), only to see that fall flat after 1 season. The same held true for their final ABC series, Mary-Kate & Ashley In Action, which lasted 1 season as well (2001-2).
The series was delayed by more than a month while ABC was trying to wrap up another DIC entry, Sabrina: The Animated Series, and, rather than have the two shows airing side-by-side for an hour's worth of "girl power" cartoons, ABC chose to cancel this animated Sabrina, a prequel to the live-action series, but ended up bidding the Olsens farewell 8 months later. Earlier, the Family Channel (now ABC Family) had picked up broadcast rights for the sisters' video series, The Adventures of Mary-Kate & Ashley, but that didn't last long, either.
On In Action, the twins are secret agents Misty (Mary-Kate) & Amber (Ashley), who travel the globe to catch the bad guys. The live-action preamble, with the girls at a Hollywood premiere for the show, was likely so that viewers knew they were voicing their animated alter-egos.
After In Action, the twins tried one last series, So Little Time, for ABC Family, but, that too was short-lived. We'll be looking at that another time. Right now, here's the open: