W.I.T.C.H. arrived on ABC in the winter of 2004-5 with a great deal of fanfare and hype, imported as it was from Italy. Unfortunately, because it didn't meet the FCC E/I requirements, ABC placed the series in the dreaded "death slot" at 12 noon (ET), where it replaced Kim Possible. The two series would alternate in the slot for the rest of the season, but, sorry to say. W.I.T.C.H. was cancelled after 1 season in the US.
The titular acronym comes from the five protagonists: Will, Irma, Taranee, Cornelia, & Hay Lin, and the series was a spin-off from an Italian comic book of the same name, which, if I remember correctly, was brought to the US by another Disney subsidiary, Hyperion, for publication here, in trade paperback form, although I could be wrong. I tried to watch the first episode, but just couldn't get into it. Winxeva uploaded the open to YouTube:
Realizing that ABC programmers' hands were tied, cable cousin ABC Family aired the series about 3 hours before the ABC broadcast, but about a week or so behind. Not that it would matter in the long run. Not to be outdone, Fox trotted out the similarly themed Winx Club that same winter, and was able to sustain it for at least a full year or two.
Yet, ever since it was cancelled here in the US, there's been no W.I.T.C.H. merchandise to be had, even second or third hand. Go figure.